Dementia Neuroscience LabDementia Neuroscience LabToward a world without dementia

Publications

Peer-reviewed articles, preprints, manuscripts in preparation, and conference abstracts spanning Alzheimer's disease and related dementias, systems neuroscience, biomarker modeling, stroke imaging analytics (including lesion–symptom mapping), clinically grounded AI, and implementation science.

About preprints

Preprints are shared for transparency and feedback and have not been certified by peer review. They report medical research that should not be used to guide clinical practice.

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Showing 50 of 50 entries.

Peer-reviewed articles

  • paper · Proceedings of the National Academy of Sciences

    2025

    Multiarea processing in body patches of the primate inferotemporal cortex implements inverse graphics

    Yilmaz H, Shah AD, Letrou A, Kumar S, Vogels R, Yildirim I

    systems neurosciencevisioninverse graphics

    Shows how body-selective patches encode 3D structure using inverse-graphics style computation across inferotemporal areas.

    View resource →
  • paper · Pediatric Neurology

    2024

    A case series analysis of pediatric LGI1 encephalitis: clinical course, challenges, and implications

    Verma K, Hardy D

    pediatric neurologyencephalitiscognitive care

    Lifespan cognitive clinic insights from a pediatric LGI1 encephalitis series, informing adult dementia care pathways.

    View resource →
  • paper · Diagnostics

    2022

    Automatic Segmentation and Quantitative Assessment of Stroke Lesions on MR Images

    Verma K, Kumar S, Paydarfar D

    strokelesion mappingdeep learningbiomarkers

    Deep-learning lesion segmentation and quantification that underpins our voxel-based lesion–symptom mapping efforts with Dell Medical School.

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  • paper · NeuroSci

    2022

    How Do We Connect Brain Areas with Cognitive Functions? The Past, the Present and the Future

    Verma K, Kumar S

    cognitionnetwork neurosciencepsychometrics

    Invited review articulating the clinic-to-cortex framework we use to interpret OASIS-3 psychometrics and neuroimaging data.

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  • paper · Cerebral Cortex Communications

    2022

    It is not just the category: behavioral effects of fMRI-guided electrical microstimulation result from a complex interplay of factors

    Kumar S, Mergen E, Vogels R

    microstimulationsystems neurosciencebehavior

    fMRI-guided microstimulation work clarifying how causal perturbations of body patches influence categorization behavior.

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  • paper · eLife

    2022

    Similar neural and perceptual masking effects of low-power optogenetic stimulation in primate V1

    Chen CY, Chen YY, Benvenuti G, Kumar S, Ramakrishnan C, Deisseroth K, Geisler WS, Seidemann E

    optogeneticsvisionsystems neuroscience

    Demonstrates matched neural and perceptual masking from low-power optogenetic stimulation in behaving primates.

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  • paper · Journal of Cognitive Neuroscience

    2019

    Body patches in inferior temporal cortex encode categories with different temporal dynamics

    Kumar S, Vogels R

    visiontemporal dynamicsinferotemporal cortex

    Single-unit recordings reveal distinct temporal dynamics across body patches that inform our phenotyping work.

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  • paper · Cerebral Cortex

    2019

    Transformation of visual representations across ventral stream body-selective patches

    Kumar S, Popivanov ID, Vogels R

    ventral streamvisionsystems neuroscience

    Quantifies how visual representations evolve from mid-STS to anterior body patches, motivating current clustering efforts.

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  • paper · eNeuro

    2017

    Shape selectivity of middle Superior Temporal Sulcus body patch neurons

    Kalfas I, Kumar S, Vogels R

    shapevisionSTS

    Co-first author work detailing single-neuron selectivity in the mid-STS body patch.

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  • paper · Molecular BioSystems

    2015

    Characterization of host response to C. neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV

    Selvan LDN, Sreenivasamurthy SK, Kumar S, Prasad TSK, et al.

    proteomicsneuroinfectionsHIV
    View resource →
  • paper · Scholars Academic Journal of Biosciences

    2015

    Comparative analysis of anthropometric parameters and lipid profile of type 2 diabetic patients in southwest Punjab

    Maria AK, Verma K, Kumar S, Gupta VK, Kumar M

    diabetesanthropometricspublic health

    Assesses cardiometabolic risk markers that now inform dementia risk profiling.

  • paper · International Journal of Applied and Basic Medical Research

    2014

    Effect of preeclampsia on insulin sensitivity

    Sinha S, Dhaliwal GS, Gupta K, Kumar S, Gupta A

    preeclampsiametabolismclinical research
    View resource →
  • paper · Clinical Proteomics

    2014

    Host response profile of human brain proteome in toxoplasma encephalitis

    Sahu A, Kumar S, Shankar SK, et al.

    proteomicsencephalitissystems biology
    View resource →
  • paper · Nucleic Acids Research

    2014

    Plasma Proteome Database as a resource for proteomics research: 2014 update

    Nanjappa V, Kumar S, Prasad TSK, et al.

    proteomicsdatabasesbioinformatics
    View resource →
  • paper · PLoS ONE

    2014

    PrediQt-Cx: Post treatment health related quality of life prediction model for cervical cancer patients

    Kumar S, Rana ML, Verma K, Singh N, Sharma AK, Maria AK, Dhaliwal GS, Khaira HK, Saini S

    predictive modelingoncologyquality of life
    View resource →
  • paper · International Journal of Collaborative Research on Internal Medicine & Public Health

    2012

    Stress leading to overweight/obesity in first MBBS hosteller girls

    Verma K, Goyal S

    stressobesitystudent health

Preprints

  • preprint · medRxiv

    2025

    Design-Induced Circularity in Alzheimer Biomarker Trials and Trial-Ready Cohorts: Enrichment, Data-Driven Selection, and Estimand Mismatch

    Kumar S, Verma K

    Alzheimer's diseasebiomarkerstrial designestimandstransportabilitybias

    Methods-focused preprint auditing 72 Alzheimer biomarker trials/cohorts and mechanistically simulating enrichment and selection–inference reuse (“double dipping”). Proposes practical safeguards (explicit target population/estimand, discovery–confirmation separation, and leakage-prevention reporting).

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  • preprint · arXiv

    2025

    Primary Care Diagnoses as a Reliable Predictor for Orthopedic Surgical Interventions

    Verma K, Michels A, Gumusaneli E, Chitnis S, Kumar S, Thompson C, Esmail L, et al.

    AIclinical decision supportorthopedics

    Validates BooksMed-derived predictors that generalize beyond neurology.

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  • preprint · arXiv

    2023

    Emulating Human Cognitive Processes for Expert-Level Medical Question-Answering with Large Language Models

    Verma K, Kumar S, Wottrich S, López KR, Aggarwal N, Bhatt Z, Singh A, et al.

    AIclinical decision supportneurology

    Introduces ExpertMedQA/BooksMed, demonstrating higher accuracy than Med-PaLM 2, Almanac, and GPT-4 on physician-scored neurology benchmarks.

    View resource →

In preparation

  • paper · Manuscript in preparation

    2025

    A fast and robust retinotopic-scale representation of occluding edges in macaque V1

    Kumar S, Chen YC, Seidemann E

    visionoptogeneticsscene segmentation

    Extends our SFN 2021 findings on V1 segmentation mechanisms.

  • paper · Manuscript in preparation

    2025

    Dementia modulates the distributed representations of cognitive functions

    Verma K, Kumar S

    psychometricsAβ-PETnetwork neuroscience

    Full manuscript expanding on the AAN/Neurology 2023 abstract using OASIS-3 data.

  • paper · Manuscript in preparation

    2025

    Disease modifying therapies in Alzheimer's: Are we there yet?

    Verma K, Kumar S

    anti-amyloidimplementation sciencereview

    Perspective on anti-amyloid rollout challenges drawn from Express Dementia Care work.

Conference presentations & abstracts

  • poster · American Academy of Neurology Annual Meeting

    2026

    Ear-Specific Word Recognition and MRI Laterality in Dementia: An Exploratory Clinic-Based Pilot

    Kumar S, Gohmert A, Burnett E, Verma K

    auditoryMRIpilot
  • poster · American Academy of Neurology Annual Meeting

    2026

    Express Dementia Care in East Texas (EDCC): An Integrated, Closed-loop Model to Shorten Time-To-Diagnosis and Improve Caregiver Outcomes

    Verma K, Voyles H, Burnett E, Kumar S, Gohmert A, Schmitt A

    care pathwaysrural healthimplementation
  • poster · American Academy of Neurology Annual Meeting

    2026

    Health Disparities and Diagnostic Challenges in Anti-Amyloid Therapy Implementation: A Rural Texas Experience

    Burnett E, Voyles H, Kumar S, Verma K

    anti-amyloidhealth equityimplementation
  • poster · American Academy of Neurology Annual Meeting

    2026

    Psychometrics and Aβ-PET Jointly Stratify Clinical Dementia Severity

    Verma K, Kumar S

    Aβ-PETpsychometricsdementia
  • poster · American Academy of Neurology Annual Meeting

    2026

    Unsupervised Clustering Reveals a Reproducible Language-Dominant Phenotype Across FTD Stages

    Kumar S, Verma K

    FTDunsupervised learninglanguage
  • poster · American Academy of Neurology Annual Meeting

    2024

    An Expert-Level Artificial Intelligence Model in Neurology Simulating Human Cognitive Processes

    Verma K, Abdurashidova M, Motina M, Wottrich S, López K, Moodley M, Kumar S, et al.

    AIclinical decision support
    View resource →
  • poster · American Academy of Neurology Annual Meeting

    2023

    Dementia Modulates the Distributed Representations of Cognitive Functions

    Verma K, Kumar S

    psychometricsnetwork neuroscience
  • poster · Neurology 100(17_suppl_2):0104

    2023

    Dementia Modulates the Distributed Representations of Cognitive Functions (P4-12.011)

    Verma K, Kumar S

    psychometricsnetwork neuroscience
    View resource →
  • poster · Texas Neurological Society Meeting

    2023

    Imaging and psychometric evidence to support clinical dementia grading

    Verma K, Kumar S

    psychometricsimplementation
  • poster · Child Neurology Society, Cincinnati

    2022

    Model development for automatic segmentation of chronic stroke lesions

    Verma K, Kumar S

    strokelesion mapping
  • poster · Society for Neuroscience Annual Meeting

    2021

    A fast and robust retinotopic-scale representation of occluding edges in macaque V1 suggests an active role for V1 in scene segmentation

    Kumar S, Chen YC, Seidemann E

    visionoptogeneticsscene segmentation
  • poster · Society for Neuroscience Annual Meeting

    2021

    Automatic segmentation of stroke lesions on MR images for voxel-based lesion-symptom mapping

    Verma K, Kumar S

    strokelesion mappingdeep learning
  • talk · Dell Medical School Cerebrovascular Research Interest Group

    2021

    How do we connect brain areas to cognitive functions?

    Verma K, Kumar S

    cognitionnetwork neuroscience
  • poster · Vision Sciences Society Annual Meeting

    2021

    Inverse graphics explains population responses in body-selective regions of the primate inferotemporal cortex

    Yilmaz H, Shah AD, Kumar S, Vogels R, Tenenbaum JB, Yildirim I

    visioninverse graphics
  • poster · Dell Medical Research Day

    2020

    Addressing subjectivity in clinical practice: A conceptual framework for quantifying patient-reported outcomes

    Verma K, Kumar S

    patient-reported outcomesimplementation
  • talk · Texas Pediatric Neuroscience Network Conference

    2020

    Epilepsy before and after surgical intervention

    Verma K, Clarke D

    epilepsypediatrics
  • talk · Cold Spring Harbor NAISys Meeting

    2020

    Inverse graphics explains population responses in body-selective regions of the primate inferotemporal cortex

    Yilmaz H, Shah AD, Kumar S, Vogels R, Tenenbaum JB, Yildirim I

    visioninverse graphics
  • poster · Society for Neuroscience Annual Meeting

    2019

    Neural and perceptual correlates of nonlinear interactions between visual and optogenetic stimulation in behaving macaque V1

    Kumar S, Chen CY, Chen YY, Benvenuti G, Whitmire MP, Geisler WS, Seidemann E

    optogeneticsvision
  • poster · Belgian Brain Congress / Frontiers in Neuroscience Abstracts

    2018

    Effect of electrical microstimulation of the anterior Superior Temporal Sulcus body patch on visual categorization tasks

    Mergan E, Kumar S, Vogels R

    STSmicrostimulation
    View resource →
  • poster · Society for Neuroscience Annual Meeting

    2018

    The effect of electrical microstimulation of a body patch on visual categorization tasks

    Kumar S, Mergen E, Vogels R

    microstimulationvision
  • poster · Journal of Vision / Vision Sciences Society Annual Meeting

    2017

    Modeling the shape selectivity of single neurons of a macaque body patch

    Kalfas I, Kumar S, Vogels R

    shapevision
    View resource →
  • poster · Society for Neuroscience Annual Meeting

    2017

    Monkey brain fMRI responses to custom-designed animations of monkey hand- and tail-grasping actions

    Vissers MM, Sharma S, Fiave PA, Kumar S, Nelissen K

    fMRImotorvision
  • poster · Society for Neuroscience Annual Meeting

    2017

    Stimulus selectivity of macaque middle and anterior superior temporal sulcus body patches

    Kumar S, Popivanov ID, Vogels R

    visionSTS
  • poster · Society for Neuroscience Annual Meeting

    2016

    Coding of viewpoint, posture and identity of bodies in the macaque midSTS body patch

    Kumar S, Vogels R

    visionSTS
  • poster · Society for Neuroscience Annual Meeting

    2016

    Increased viewpoint-tolerant coding of body posture and identity in the anterior compared to the midSTS body patch

    Vogels R, Kumar S

    visionSTS
  • poster · Society for Neuroscience Annual Meeting

    2015

    Neural encoding of shapes in the middle superior temporal sulcus (mid-STS) body patch neurons

    Kumar S, Vogels R

    visionSTS
  • poster · Belgian Society for Neuroscience / Frontiers in Neuroscience

    2015

    Single unit feature selectivity of the midSTS body patch: adaptive stimulus sampling and modeling

    Kumar S, Vogels R

    visionSTS
    View resource →
  • talk · KARMIC – Annual International Medical Research Conference

    2013

    Results of the project Malnutrition and Developmental Milestones (MDM)

    Verma K, Kumar S

    developmentnutrition